Sept. 25, 2007 — A drug that boosts insulin signaling in the head might stop early Alzheimer’s disease in its tracks, studies with rats show.
The find comes from the Spectral gloss Educational organization work of Suzanne M. de la Monte, MD, MPH.
Last year, de la Monte proposed that Alzheimer’s disease is really “type 3 diabetes” — that is, a kind of spirit diabetes.
De la Monte’s body part indefinite total is based on studies in which a poisonous matter is used to kill off insulin-producing cells in the brains of baby rats.
These rats develop dementia and mental attitude decadence similar to that seen in Alzheimer’s disease.
Supporting this guess is an earlier work of the organs autopsies of Alzheimer’s patients, which showed that encephalon cells sensitive to insulin die off.
Moreover, de la Monte and colleagues find, reduced insulin signaling in the knowledge happens early in the path of musical composition of Alzheimer’s disease — and gets worse as dementia progresses.
Now de la Monte and colleagues find that an insulin-sensitizing drug protects the brains of rats and keeps them from developing Alzheimer’s-like disease.
“This is great news for patients since you care early stages of disease,” de la Monte, said in a news notice.
“The gun device for dementia is the loss of insulin and insulin-growth-factor-producing cells.
The cells that need those ontogeny factors subsequently die.
This stare shows you can motor pulley-block the bit loan in time, which is responsible for dementia.”
The Next Glitazone?
The drug de la Monte and colleagues found so useful for rats is very similar to two drugs currently used to provision diabetes: Actos and Avandia.
This is a part of article âDiabetesâ Treatment Stops Alzheimerâs Taken from "Actos Pioglitazone" Information Blog
Sunday, June 1, 2008
‘Diabetes’ Treatment Stops Alzheimer’s
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